TY  - GEN
AU  - Tharakaraman,Kannan
AU  - Watanabe,Satoru
AU  - Chan,Kuan Rong
AU  - Huan,Jia
AU  - Subramanian,Vidya
AU  - Chionh,Yok Hian
AU  - Raguram,Aditya
AU  - Quinlan,Devin
AU  - McBee,Megan
AU  - Ong,Eugenia Z
AU  - Gan,Esther S
AU  - Tan,Hwee Cheng
AU  - Tyagi,Anu
AU  - Bhushan,Shashi
AU  - Lescar,Julien
AU  - Vasudevan,Subhash G
AU  - Ooi,Eng Eong
AU  - Sasisekharan,Ram
TI  - Rational Engineering and Characterization of an mAb that Neutralizes Zika Virus by Targeting a Mutationally Constrained Quaternary Epitope
SN  - 1934-6069
PY  - 2018///0928
KW  - Animals
KW  - Antibodies, Monoclonal
KW  - administration & dosage
KW  - Antibodies, Neutralizing
KW  - Antibodies, Viral
KW  - Dengue Virus
KW  - immunology
KW  - Disease Models, Animal
KW  - Epitopes
KW  - chemistry
KW  - Female
KW  - Male
KW  - Mice
KW  - Models, Molecular
KW  - Neutralization Tests
KW  - methods
KW  - Pregnancy
KW  - Protein Engineering
KW  - Protein Structure, Quaternary
KW  - Treatment Outcome
KW  - Viral Envelope Proteins
KW  - Viremia
KW  - drug therapy
KW  - Zika Virus
KW  - genetics
KW  - Zika Virus Infection
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.chom.2018.04.004
ER  -