TY  - GEN
AU  - Cheung,S Y A
AU  - Parkinson,J
AU  - Wählby-Hamrén,U
AU  - Dota,C D
AU  - Kragh,Å M
AU  - Bergenholm,L
AU  - Vik,T
AU  - Collins,T
AU  - Arfvidsson,C
AU  - Pollard,C E
AU  - Tomkinson,H K
AU  - Hamrén,B
TI  - A tutorial on model informed approaches to cardiovascular safety with focus on cardiac repolarisation
SN  - 1573-8744
PY  - 2019///1003
KW  - Animals
KW  - Blood Pressure
KW  - drug effects
KW  - Cardiovascular Diseases
KW  - chemically induced
KW  - Cardiovascular System
KW  - Dogs
KW  - Drug Discovery
KW  - methods
KW  - Drug Evaluation, Preclinical
KW  - Drug-Related Side Effects and Adverse Reactions
KW  - etiology
KW  - Guinea Pigs
KW  - Heart Rate
KW  - Humans
KW  - Macaca mulatta
KW  - Pharmaceutical Preparations
KW  - administration & dosage
KW  - Rabbits
KW  - Rats
N1  - Publication Type: Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1007/s10928-018-9589-6
ER  -