Mahmoud, Mahmoud A Abdelaziz

Heterocyclization of Thiophenes Derived from Estrone Followed by Cytotoxic, HTRF Kinase and Pim-1 Kinase Evaluations. [electronic resource] - Anti-cancer agents in medicinal chemistry 2018 - 1711-1728 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1875-5992

10.2174/1871520618666180507141045 doi


Antineoplastic Agents--chemical synthesis
Cell Line, Tumor
Cell Proliferation--drug effects
Dose-Response Relationship, Drug
Drug Screening Assays, Antitumor
Humans
Molecular Structure
Protein Kinase Inhibitors--chemical synthesis
Protein-Tyrosine Kinases--antagonists & inhibitors
Proto-Oncogene Proteins c-pim-1--antagonists & inhibitors
Structure-Activity Relationship
Thiophenes--chemical synthesis