Germline Duplication of SNORA18L5 Increases Risk for HBV-related Hepatocellular Carcinoma by Altering Localization of Ribosomal Proteins and Decreasing Levels of p53. [electronic resource]
- Gastroenterology 08 2018
- 542-556 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1528-0012
10.1053/j.gastro.2018.04.020 doi
Adult Animals Asian People--genetics Carcinoma, Hepatocellular--genetics Cell Line, Tumor Cell Proliferation--genetics Chromosomes, Human, Pair 15--genetics DNA Copy Number Variations--genetics Female Gene Duplication Gene Expression Regulation, Neoplastic--genetics Gene Knockdown Techniques Genome-Wide Association Study Hepatitis B virus--isolation & purification Hepatitis B, Chronic--genetics Humans Liver--pathology Liver Neoplasms--genetics Male Mice Mice, Nude Middle Aged RNA, Small Interfering--metabolism RNA, Small Nucleolar--genetics Ribosomal Proteins--metabolism Tumor Suppressor Protein p53--genetics Xenograft Model Antitumor Assays