Design, Synthesis, and Testing of Potent, Selective Hepsin Inhibitors via Application of an Automated Closed-Loop Optimization Platform. [electronic resource]
- Journal of medicinal chemistry 05 2018
- 4335-4347 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1520-4804
10.1021/acs.jmedchem.7b01698 doi
Breast Neoplasms--drug therapy Cell Proliferation--drug effects Drug Design Enzyme Inhibitors--chemistry Female High-Throughput Screening Assays--standards Humans Models, Molecular Molecular Structure Protein Conformation Serine Endopeptidases--chemistry Tumor Cells, Cultured