Moran, Sean P <br/><br/>
PF-06827443 Displays Robust Allosteric Agonist and Positive Allosteric Modulator Activity in High Receptor Reserve and Native Systems.  [electronic resource] 

 -  ACS chemical neuroscience  09 2018 
 - 2218-2224 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1948-7193 
<br/><br/><label>Standard No.: </label>10.1021/acschemneuro.8b00106  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Allosteric Regulation<br/>Animals<br/>CHO Cells<br/>Calcium--metabolism<br/>Cricetulus<br/>Dogs<br/>Humans<br/>Isoindoles--pharmacology<br/>Mice<br/>Oxazoles--pharmacology<br/>Patch-Clamp Techniques<br/>Prefrontal Cortex--drug effects<br/>Rats<br/>Receptor, Muscarinic M1--agonists<br/>Seizures--chemically induced