TY  - GEN
AU  - Antonic,Ana
AU  - Dottori,Mirella
AU  - Macleod,Malcolm R
AU  - Donnan,Geoffrey A
AU  - Howells,David W
TI  - NXY-059, a Failed Stroke Neuroprotectant, Offers No Protection to Stem Cell-Derived Human Neurons
SN  - 1532-8511
PY  - 2018///1022
KW  - Benzenesulfonates
KW  - pharmacology
KW  - Cell Death
KW  - drug effects
KW  - Cell Hypoxia
KW  - Cell Survival
KW  - Cells, Cultured
KW  - Coculture Techniques
KW  - Dose-Response Relationship, Drug
KW  - Drug Evaluation, Preclinical
KW  - Embryonic Stem Cells
KW  - Fibroblasts
KW  - physiology
KW  - Glucose
KW  - deficiency
KW  - Humans
KW  - Hydrogen Peroxide
KW  - toxicity
KW  - L-Lactate Dehydrogenase
KW  - metabolism
KW  - Neurons
KW  - Neuroprotective Agents
KW  - Nitroprusside
KW  - Oxidative Stress
KW  - Single-Blind Method
KW  - Treatment Failure
N1  - Publication Type: Journal Article; Randomized Controlled Trial
UR  - https://doi.org/10.1016/j.jstrokecerebrovasdis.2018.03.015
ER  -