Antonic, Ana

NXY-059, a Failed Stroke Neuroprotectant, Offers No Protection to Stem Cell-Derived Human Neurons. [electronic resource] - Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association Aug 2018 - 2158-2165 p. digital

Publication Type: Journal Article; Randomized Controlled Trial

1532-8511

10.1016/j.jstrokecerebrovasdis.2018.03.015 doi


Benzenesulfonates--pharmacology
Cell Death--drug effects
Cell Hypoxia--drug effects
Cell Survival--drug effects
Cells, Cultured
Coculture Techniques
Dose-Response Relationship, Drug
Drug Evaluation, Preclinical
Embryonic Stem Cells--drug effects
Fibroblasts--physiology
Glucose--deficiency
Humans
Hydrogen Peroxide--toxicity
L-Lactate Dehydrogenase--metabolism
Neurons--drug effects
Neuroprotective Agents--pharmacology
Nitroprusside--toxicity
Oxidative Stress--drug effects
Single-Blind Method
Treatment Failure