Turk, Anita A
PARP inhibitors in breast cancer: Bringing synthetic lethality to the bedside. [electronic resource]
- Cancer 06 2018
- 2498-2506 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Review
1097-0142
10.1002/cncr.31307 doi
Antineoplastic Agents, Immunological--pharmacology
Antineoplastic Combined Chemotherapy Protocols--pharmacology
BRCA1 Protein--genetics
BRCA2 Protein--genetics
Breast Neoplasms--drug therapy
Cell Survival--drug effects
Clinical Trials as Topic
DNA Repair--drug effects
Drug Resistance, Neoplasm--drug effects
Female
Humans
Molecular Targeted Therapy--methods
Patient Selection
Poly(ADP-ribose) Polymerase Inhibitors--pharmacology
Poly(ADP-ribose) Polymerases--metabolism
Synthetic Lethal Mutations
Treatment Outcome