Turk, Anita A

PARP inhibitors in breast cancer: Bringing synthetic lethality to the bedside. [electronic resource] - Cancer 06 2018 - 2498-2506 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Review

1097-0142

10.1002/cncr.31307 doi


Antineoplastic Agents, Immunological--pharmacology
Antineoplastic Combined Chemotherapy Protocols--pharmacology
BRCA1 Protein--genetics
BRCA2 Protein--genetics
Breast Neoplasms--drug therapy
Cell Survival--drug effects
Clinical Trials as Topic
DNA Repair--drug effects
Drug Resistance, Neoplasm--drug effects
Female
Humans
Molecular Targeted Therapy--methods
Patient Selection
Poly(ADP-ribose) Polymerase Inhibitors--pharmacology
Poly(ADP-ribose) Polymerases--metabolism
Synthetic Lethal Mutations
Treatment Outcome