TY  - GEN
AU  - Agarwal,Sameer
AU  - Sasane,Santosh
AU  - Kumar,Jeevan
AU  - Deshmukh,Prashant
AU  - Bhayani,Hitesh
AU  - Giri,Poonam
AU  - Giri,Suresh
AU  - Soman,Shubhangi
AU  - Kulkarni,Neelima
AU  - Jain,Mukul
TI  - Evaluation of novel TGR5 agonist in combination with Sitagliptin for possible treatment of type 2 diabetes
SN  - 1464-3405
PY  - 2018///1227
KW  - Animals
KW  - Binding Sites
KW  - Diabetes Mellitus, Type 2
KW  - drug therapy
KW  - Drug Therapy, Combination
KW  - Female
KW  - Glucagon-Like Peptide 1
KW  - metabolism
KW  - Half-Life
KW  - Humans
KW  - Hypoglycemic Agents
KW  - chemistry
KW  - Imidazoles
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Molecular Docking Simulation
KW  - Protein Structure, Tertiary
KW  - Receptors, G-Protein-Coupled
KW  - agonists
KW  - Sitagliptin Phosphate
KW  - therapeutic use
KW  - Structure-Activity Relationship
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.bmcl.2018.04.011
ER  -