TY - GEN AU - Italiano,Antoine AU - Soria,Jean-Charles AU - Toulmonde,Maud AU - Michot,Jean-Marie AU - Lucchesi,Carlo AU - Varga,Andrea AU - Coindre,Jean-Michel AU - Blakemore,Stephen J AU - Clawson,Alicia AU - Suttle,Benjamin AU - McDonald,Alice A AU - Woodruff,Mark AU - Ribich,Scott AU - Hedrick,Eric AU - Keilhack,Heike AU - Thomson,Blythe AU - Owa,Takashi AU - Copeland,Robert A AU - Ho,Peter T C AU - Ribrag,Vincent TI - Tazemetostat, an EZH2 inhibitor, in relapsed or refractory B-cell non-Hodgkin lymphoma and advanced solid tumours: a first-in-human, open-label, phase 1 study SN - 1474-5488 PY - 2019///0409 KW - Aged KW - Antineoplastic Agents KW - administration & dosage KW - Benzamides KW - Biphenyl Compounds KW - Dose-Response Relationship, Drug KW - Enhancer of Zeste Homolog 2 Protein KW - antagonists & inhibitors KW - Enzyme Inhibitors KW - Female KW - France KW - Humans KW - Lymphoma, B-Cell KW - drug therapy KW - Male KW - Maximum Tolerated Dose KW - Middle Aged KW - Morpholines KW - Pyridones KW - Time Factors KW - Treatment Outcome N1 - Publication Type: Clinical Trial, Phase I; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/S1470-2045(18)30145-1 ER -