TY - GEN AU - Doud,Michael B AU - Lee,Juhye M AU - Bloom,Jesse D TI - How single mutations affect viral escape from broad and narrow antibodies to H1 influenza hemagglutinin SN - 2041-1723 PY - 2018///1121 KW - Amino Acid Sequence KW - Antibodies, Monoclonal KW - chemistry KW - Antibodies, Neutralizing KW - Antibodies, Viral KW - Antibody Specificity KW - Binding Sites KW - Crystallography, X-Ray KW - Gene Expression KW - HEK293 Cells KW - Hemagglutinin Glycoproteins, Influenza Virus KW - Humans KW - Immune Evasion KW - Influenza A Virus, H1N1 Subtype KW - Kinetics KW - Models, Molecular KW - Mutation KW - Neutralization Tests KW - Protein Binding KW - Protein Conformation, alpha-Helical KW - Protein Conformation, beta-Strand KW - Protein Interaction Domains and Motifs KW - Recombinant Proteins KW - Thermodynamics N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/s41467-018-03665-3 ER -