Use of physiologically based kinetic modelling-facilitated reverse dosimetry to convert in vitro cytotoxicity data to predicted in vivo liver toxicity of lasiocarpine and riddelliine in rat. [electronic resource]
- Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association Jun 2018
- 216-226 p. digital
Publication Type: Journal Article
1873-6351
10.1016/j.fct.2018.04.012 doi
Animals Cells, Cultured Dose-Response Relationship, Drug Hepatocytes--drug effects Liver--cytology Male Mice Models, Biological Pyrrolizidine Alkaloids--blood Rats, Sprague-Dawley Tissue Distribution Toxicity Tests, Acute