TY - GEN AU - Menhaji-Klotz,Elnaz AU - Hesp,Kevin D AU - Londregan,Allyn T AU - Kalgutkar,Amit S AU - Piotrowski,David W AU - Boehm,Markus AU - Song,Kun AU - Ryder,Tim AU - Beaumont,Kevin AU - Jones,Rhys M AU - Atkinson,Karen AU - Brown,Janice A AU - Litchfield,John AU - Xiao,Jun AU - Canterbury,Daniel P AU - Burford,Kristen AU - Thuma,Benjamin A AU - Limberakis,Chris AU - Jiao,Wenhua AU - Bagley,Scott W AU - Agarwal,Saket AU - Crowell,Danielle AU - Pazdziorko,Stephen AU - Ward,Jessica AU - Price,David A AU - Clerin,Valerie TI - Discovery of a Novel Small-Molecule Modulator of C-X-C Chemokine Receptor Type 7 as a Treatment for Cardiac Fibrosis SN - 1520-4804 PY - 2019///0423 KW - Acetamides KW - chemical synthesis KW - Animals KW - Azepines KW - Cardiotonic Agents KW - Dogs KW - Fibrosis KW - chemically induced KW - Heart Diseases KW - Humans KW - Hydrophobic and Hydrophilic Interactions KW - Isoproterenol KW - Madin Darby Canine Kidney Cells KW - Male KW - Mice, Inbred BALB C KW - Mice, Inbred C57BL KW - Microsomes, Liver KW - metabolism KW - Molecular Structure KW - Receptors, CXCR KW - Structure-Activity Relationship N1 - Publication Type: Journal Article UR - https://doi.org/10.1021/acs.jmedchem.8b00190 ER -