TY  - GEN
AU  - Local,Andrea
AU  - Zhang,Hongying
AU  - Benbatoul,Khalid D
AU  - Folger,Peter
AU  - Sheng,Xia
AU  - Tsai,Cheng-Yu
AU  - Howell,Stephen B
AU  - Rice,William G
TI  - APTO-253 Stabilizes G-quadruplex DNA, Inhibits MYC Expression, and Induces DNA Damage in Acute Myeloid Leukemia Cells
SN  - 1538-8514
PY  - 2019///0625
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Apoptosis
KW  - drug effects
KW  - Cell Cycle Checkpoints
KW  - Cell Line, Tumor
KW  - Cell Survival
KW  - Cyclin-Dependent Kinase Inhibitor p21
KW  - genetics
KW  - DNA Damage
KW  - Dose-Response Relationship, Drug
KW  - G-Quadruplexes
KW  - Gene Expression Regulation, Neoplastic
KW  - Humans
KW  - Imidazoles
KW  - Leukemia, Myeloid, Acute
KW  - Phenanthrolines
KW  - Proto-Oncogene Proteins c-myc
KW  - chemistry
KW  - Signal Transduction
KW  - Stress, Physiological
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1158/1535-7163.MCT-17-1209
ER  -