TY - GEN AU - Wild,Christopher T AU - Miszkiel,Joanna M AU - Wold,Eric A AU - Soto,Claudia A AU - Ding,Chunyong AU - Hartley,Rachel M AU - White,Mark A AU - Anastasio,Noelle C AU - Cunningham,Kathryn A AU - Zhou,Jia TI - Design, Synthesis, and Characterization of 4-Undecylpiperidine-2-carboxamides as Positive Allosteric Modulators of the Serotonin (5-HT) 5-HT SN - 1520-4804 PY - 2019///1014 KW - Allosteric Regulation KW - Allosteric Site KW - Amides KW - chemical synthesis KW - Animals KW - Azepines KW - chemistry KW - CHO Cells KW - Calcium KW - metabolism KW - Cricetinae KW - Cricetulus KW - Drug Design KW - Half-Life KW - Indoles KW - Locomotion KW - drug effects KW - Molecular Docking Simulation KW - Piperidines KW - Protein Isoforms KW - Protein Structure, Tertiary KW - Rats KW - Receptor, Serotonin, 5-HT2C KW - Serotonin 5-HT2 Receptor Agonists KW - Structure-Activity Relationship N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1021/acs.jmedchem.8b00401 ER -