TY - GEN AU - Patel,Shivani AU - Modi,Palmi AU - Ranjan,Vishal AU - Chhabria,Mahesh TI - Structure-based design, synthesis and evaluation of 2,4-diaminopyrimidine derivatives as novel caspase-1 inhibitors SN - 1090-2120 PY - 2019///0128 KW - Caspase 1 KW - metabolism KW - Caspase Inhibitors KW - chemical synthesis KW - Dose-Response Relationship, Drug KW - Drug Design KW - Humans KW - Molecular Docking Simulation KW - Molecular Structure KW - Pyrimidines KW - Structure-Activity Relationship KW - THP-1 Cells N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/j.bioorg.2018.03.019 ER -