Patel, Shivani <br/><br/>
Structure-based design, synthesis and evaluation of 2,4-diaminopyrimidine derivatives as novel caspase-1 inhibitors.  [electronic resource] 

 -  Bioorganic chemistry  08 2018 
 - 258-268 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1090-2120 
<br/><br/><label>Standard No.: </label>10.1016/j.bioorg.2018.03.019  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Caspase 1--metabolism<br/>Caspase Inhibitors--chemical synthesis<br/>Dose-Response Relationship, Drug<br/>Drug Design<br/>Humans<br/>Molecular Docking Simulation<br/>Molecular Structure<br/>Pyrimidines--chemical synthesis<br/>Structure-Activity Relationship<br/>THP-1 Cells