Chen, Shuliang <br/><br/>
SAMHD1 suppresses innate immune responses to viral infections and inflammatory stimuli by inhibiting the NF-κB and interferon pathways.  [electronic resource] 

 -  Proceedings of the National Academy of Sciences of the United States of America  04 2018 
 - E3798-E3807 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. 
<br/><br/><label>ISSN: </label>1091-6490 
<br/><br/><label>Standard No.: </label>10.1073/pnas.1801213115  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Cells, Cultured<br/>Down-Regulation<br/>Gene Expression Regulation--drug effects<br/>Gene Silencing<br/>HEK293 Cells<br/>HIV--physiology<br/>Humans<br/>I-kappa B Kinase--antagonists & inhibitors<br/>Immunity, Innate<br/>Inflammation--immunology<br/>Interferon Regulatory Factor-7--antagonists & inhibitors<br/>Interferon-alpha--biosynthesis<br/>Macrophages--immunology<br/>Male<br/>Mice<br/>NF-KappaB Inhibitor alpha--metabolism<br/>NF-kappa B--metabolism<br/>Phosphorylation<br/>Protein Processing, Post-Translational<br/>Recombinant Proteins--immunology<br/>SAM Domain and HD Domain-Containing Protein 1--physiology<br/>Sendai virus--physiology<br/>Signal Transduction--immunology<br/>THP-1 Cells<br/>Virus Diseases--immunology