TY - GEN AU - Nabet,Behnam AU - Roberts,Justin M AU - Buckley,Dennis L AU - Paulk,Joshiawa AU - Dastjerdi,Shiva AU - Yang,Annan AU - Leggett,Alan L AU - Erb,Michael A AU - Lawlor,Matthew A AU - Souza,Amanda AU - Scott,Thomas G AU - Vittori,Sarah AU - Perry,Jennifer A AU - Qi,Jun AU - Winter,Georg E AU - Wong,Kwok-Kin AU - Gray,Nathanael S AU - Bradner,James E TI - The dTAG system for immediate and target-specific protein degradation SN - 1552-4469 PY - 2019///0513 KW - Alleles KW - Animals KW - CRISPR-Cas Systems KW - Cell Cycle Proteins KW - Cell Proliferation KW - Cytoplasm KW - metabolism KW - Dimerization KW - Gene Knock-In Techniques KW - HEK293 Cells KW - Homeostasis KW - Humans KW - Ligands KW - Mice KW - Mutation KW - NIH 3T3 Cells KW - Nuclear Proteins KW - chemistry KW - Protein Binding KW - Protein Domains KW - Proteolysis KW - Proteomics KW - Proto-Oncogene Proteins p21(ras) KW - genetics KW - Signal Transduction KW - Tacrolimus Binding Protein 1A KW - Transcription Factors KW - Transgenes N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/s41589-018-0021-8 ER -