Rohde, Jason M <br/><br/>
Discovery and optimization of piperazine-1-thiourea-based human phosphoglycerate dehydrogenase inhibitors.  [electronic resource] 

 -  Bioorganic & medicinal chemistry  05 2018 
 - 1727-1739 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1464-3391 
<br/><br/><label>Standard No.: </label>10.1016/j.bmc.2018.02.016  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Dose-Response Relationship, Drug<br/>Drug Discovery<br/>Enzyme Inhibitors--chemical synthesis<br/>High-Throughput Screening Assays<br/>Humans<br/>Molecular Structure<br/>Phosphoglycerate Dehydrogenase--antagonists & inhibitors<br/>Piperazines--chemical synthesis<br/>Structure-Activity Relationship<br/>Thiourea--analogs & derivatives