TY  - GEN
AU  - Helliwell,Matthew V
AU  - Zhang,Yihong
AU  - El Harchi,Aziza
AU  - Du,Chunyun
AU  - Hancox,Jules C
AU  - Dempsey,Christopher E
TI  - Structural implications of hERG K
SN  - 1083-351X
PY  - 2019///0128
KW  - Alanine
KW  - chemistry
KW  - Computer Simulation
KW  - Cryoelectron Microscopy
KW  - Crystallography, X-Ray
KW  - Dose-Response Relationship, Drug
KW  - ERG1 Potassium Channel
KW  - antagonists & inhibitors
KW  - HEK293 Cells
KW  - Humans
KW  - Inhibitory Concentration 50
KW  - Ion Channel Gating
KW  - drug effects
KW  - Molecular Docking Simulation
KW  - Mutation
KW  - Patch-Clamp Techniques
KW  - Phenylalanine
KW  - Potassium Channel Blockers
KW  - administration & dosage
KW  - Protein Binding
KW  - Protein Conformation
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1074/jbc.RA117.000363
ER  -