Vázquez-Gómez, G <br/><br/>
Benzo[a]pyrene activates an AhR/Src/ERK axis that contributes to CYP1A1 induction and stable DNA adducts formation in lung cells.  [electronic resource] 

 -  Toxicology letters  Jun 2018 
 - 54-62 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1879-3169 
<br/><br/><label>Standard No.: </label>10.1016/j.toxlet.2018.03.012  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Active Transport, Cell Nucleus--drug effects<br/>Basic Helix-Loop-Helix Transcription Factors--agonists<br/>Benzo(a)pyrene--toxicity<br/>Bronchi--drug effects<br/>Carcinogens, Environmental--toxicity<br/>Cell Line<br/>Cell Survival--drug effects<br/>Cytochrome P-450 CYP1A1--chemistry<br/>DNA Adducts--chemistry<br/>Enzyme Activation--drug effects<br/>Enzyme Induction--drug effects<br/>Humans<br/>Hydrophobic and Hydrophilic Interactions<br/>Kinetics<br/>MAP Kinase Signaling System--drug effects<br/>Phosphorylation--drug effects<br/>Protein Kinase Inhibitors--pharmacology<br/>Protein Processing, Post-Translational--drug effects<br/>Proto-Oncogene Proteins pp60(c-src)--chemistry<br/>Receptors, Aryl Hydrocarbon--agonists<br/>Respiratory Mucosa--drug effects