TY - GEN AU - Boyarskikh,Ulyana AU - Pintus,Sergey AU - Mandrik,Nikita AU - Stelmashenko,Daria AU - Kiselev,Ilya AU - Evshin,Ivan AU - Sharipov,Ruslan AU - Stegmaier,Philip AU - Kolpakov,Fedor AU - Filipenko,Maxim AU - Kel,Alexander TI - Computational master-regulator search reveals mTOR and PI3K pathways responsible for low sensitivity of NCI-H292 and A427 lung cancer cell lines to cytotoxic action of p53 activator Nutlin-3 SN - 1755-8794 PY - 2019///0607 KW - Apoptosis KW - Cell Proliferation KW - Drug Resistance, Neoplasm KW - Humans KW - Imidazoles KW - pharmacology KW - Lung Neoplasms KW - drug therapy KW - Phosphatidylinositol 3-Kinases KW - genetics KW - Piperazines KW - Protein Kinase Inhibitors KW - Signal Transduction KW - TOR Serine-Threonine Kinases KW - Tumor Cells, Cultured KW - Tumor Suppressor Protein p53 N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1186/s12920-018-0330-5 ER -