TY - GEN AU - Tang,Tao-Tao AU - Lv,Lin-Li AU - Pan,Ming-Ming AU - Wen,Yi AU - Wang,Bin AU - Li,Zuo-Lin AU - Wu,Min AU - Wang,Feng-Mei AU - Crowley,Steve D AU - Liu,Bi-Cheng TI - Hydroxychloroquine attenuates renal ischemia/reperfusion injury by inhibiting cathepsin mediated NLRP3 inflammasome activation SN - 2041-4889 PY - 2019///1217 KW - Acute Kidney Injury KW - drug therapy KW - Animals KW - Anti-Inflammatory Agents KW - metabolism KW - Cathepsin B KW - Cathepsin L KW - Cell Line KW - Cell Survival KW - drug effects KW - Creatinine KW - blood KW - Disease Models, Animal KW - Hepatitis A Virus Cellular Receptor 1 KW - Humans KW - Hydroxychloroquine KW - Inflammasomes KW - Macrophages KW - Male KW - Mice KW - Mice, Inbred C57BL KW - NF-kappa B KW - NLR Family, Pyrin Domain-Containing 3 Protein KW - Neutrophil Infiltration KW - Reperfusion Injury N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/s41419-018-0378-3 ER -