TY - GEN AU - Wong,Yao Liang AU - LeBon,Lauren AU - Edalji,Rohinton AU - Lim,Hock Ben AU - Sun,Chaohong AU - Sidrauski,Carmela TI - The small molecule ISRIB rescues the stability and activity of Vanishing White Matter Disease eIF2B mutant complexes SN - 2050-084X PY - 2019///0709 KW - Acetamides KW - metabolism KW - Cell Line KW - Cyclohexylamines KW - Enzyme Activators KW - Eukaryotic Initiation Factor-2B KW - genetics KW - Humans KW - Leukoencephalopathies KW - Mutant Proteins KW - Neuroprotective Agents N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.7554/eLife.32733 ER -