AG490, a JAK2-specific inhibitor, downregulates the expression and activity of organic anion transporter-3. [electronic resource]
- Journal of pharmacological sciences Mar 2018
- 142-148 p. digital
Publication Type: Journal Article
1347-8648
10.1016/j.jphs.2018.01.006 doi
Animals COS Cells Chlorocebus aethiops Dose-Response Relationship, Drug Down-Regulation--drug effects Estrone--analogs & derivatives Gene Expression--drug effects Janus Kinase 2--antagonists & inhibitors Kidney--metabolism Nedd4 Ubiquitin Protein Ligases--metabolism Organic Anion Transporters, Sodium-Independent--genetics Phosphorylation--drug effects Protein Kinase Inhibitors--pharmacology Time Factors Tyrphostins--pharmacology Ubiquitination--drug effects