TY  - GEN
AU  - Kany,Andreas M
AU  - Sikandar,Asfandyar
AU  - Haupenthal,Jörg
AU  - Yahiaoui,Samir
AU  - Maurer,Christine K
AU  - Proschak,Ewgenij
AU  - Köhnke,Jesko
AU  - Hartmann,Rolf W
TI  - Binding Mode Characterization and Early in Vivo Evaluation of Fragment-Like Thiols as Inhibitors of the Virulence Factor LasB from Pseudomonas aeruginosa
SN  - 2373-8227
PY  - 2019///0911
KW  - Animals
KW  - Anti-Bacterial Agents
KW  - chemical synthesis
KW  - Bacterial Proteins
KW  - antagonists & inhibitors
KW  - Binding Sites
KW  - Cell Line
KW  - Chromatography, Liquid
KW  - Drug Evaluation, Preclinical
KW  - Drug Resistance, Bacterial
KW  - Humans
KW  - Mass Spectrometry
KW  - Metalloendopeptidases
KW  - Models, Molecular
KW  - Molecular Conformation
KW  - Molecular Structure
KW  - Moths
KW  - microbiology
KW  - Protein Binding
KW  - Pseudomonas aeruginosa
KW  - drug effects
KW  - Structure-Activity Relationship
KW  - Sulfhydryl Compounds
KW  - Virulence Factors
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1021/acsinfecdis.8b00010
ER  -