TY - GEN AU - Floc'h,Nicolas AU - Martin,Matthew J AU - Riess,Jonathan W AU - Orme,Jonathan P AU - Staniszewska,Anna D AU - Ménard,Ludovic AU - Cuomo,Maria Emanuela AU - O'Neill,Daniel J AU - Ward,Richard A AU - Finlay,M Raymond V AU - McKerrecher,Darren AU - Cheng,Mingshan AU - Vang,Daniel P AU - Burich,Rebekah A AU - Keck,James G AU - Gandara,David R AU - Mack,Philip C AU - Cross,Darren A E TI - Antitumor Activity of Osimertinib, an Irreversible Mutant-Selective EGFR Tyrosine Kinase Inhibitor, in NSCLC Harboring EGFR Exon 20 Insertions SN - 1538-8514 PY - 2019///0708 KW - Acrylamides KW - Aniline Compounds KW - Animals KW - COS Cells KW - Carcinoma, Non-Small-Cell Lung KW - drug therapy KW - Cell Line, Tumor KW - Chlorocebus aethiops KW - ErbB Receptors KW - antagonists & inhibitors KW - Exons KW - genetics KW - Female KW - Humans KW - Lung Neoplasms KW - Mice, SCID KW - Mutation KW - Piperazines KW - pharmacology KW - Protein Kinase Inhibitors KW - Xenograft Model Antitumor Assays KW - methods N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1158/1535-7163.MCT-17-0758 ER -