TY - GEN AU - Zhao,Na AU - Cao,Jin AU - Xu,Longyong AU - Tang,Qianzi AU - Dobrolecki,Lacey E AU - Lv,Xiangdong AU - Talukdar,Manisha AU - Lu,Yang AU - Wang,Xiaoran AU - Hu,Dorothy Z AU - Shi,Qing AU - Xiang,Yu AU - Wang,Yunfei AU - Liu,Xia AU - Bu,Wen AU - Jiang,Yi AU - Li,Mingzhou AU - Gong,Yingyun AU - Sun,Zheng AU - Ying,Haoqiang AU - Yuan,Bo AU - Lin,Xia AU - Feng,Xin-Hua AU - Hartig,Sean M AU - Li,Feng AU - Shen,Haifa AU - Chen,Yiwen AU - Han,Leng AU - Zeng,Qingping AU - Patterson,John B AU - Kaipparettu,Benny Abraham AU - Putluri,Nagireddy AU - Sicheri,Frank AU - Rosen,Jeffrey M AU - Lewis,Michael T AU - Chen,Xi TI - Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer SN - 1558-8238 PY - 2019///0910 KW - Animals KW - Breast Neoplasms KW - drug therapy KW - Cell Line, Tumor KW - Docetaxel KW - pharmacology KW - Drug Delivery Systems KW - Endoribonucleases KW - genetics KW - Female KW - Humans KW - Mice KW - Protein Serine-Threonine Kinases KW - Proto-Oncogene Proteins c-myc KW - Response Elements KW - Saccharomyces cerevisiae KW - Signal Transduction KW - drug effects KW - Unfolded Protein Response KW - X-Box Binding Protein 1 KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1172/JCI95873 ER -