Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer. [electronic resource]
- The Journal of clinical investigation 04 2018
- 1283-1299 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1558-8238
10.1172/JCI95873 doi
Animals Breast Neoplasms--drug therapy Cell Line, Tumor Docetaxel--pharmacology Drug Delivery Systems Endoribonucleases--genetics Female Humans Mice Protein Serine-Threonine Kinases--genetics Proto-Oncogene Proteins c-myc--genetics Response Elements Saccharomyces cerevisiae Signal Transduction--drug effects Unfolded Protein Response--drug effects X-Box Binding Protein 1--genetics Xenograft Model Antitumor Assays