TY  - GEN
AU  - Gonzalez Herrera,Karina N
AU  - Zaganjor,Elma
AU  - Ishikawa,Yoshinori
AU  - Spinelli,Jessica B
AU  - Yoon,Haejin
AU  - Lin,Jia-Ren
AU  - Satterstrom,F Kyle
AU  - Ringel,Alison
AU  - Mulei,Stacy
AU  - Souza,Amanda
AU  - Gorham,Joshua M
AU  - Benson,Craig C
AU  - Seidman,Jonathan G
AU  - Sorger,Peter K
AU  - Clish,Clary B
AU  - Haigis,Marcia C
TI  - Small-Molecule Screen Identifies De Novo Nucleotide Synthesis as a Vulnerability of Cells Lacking SIRT3
SN  - 2211-1247
PY  - 2019///0527
KW  - Amino Acid Sequence
KW  - Animals
KW  - Azaserine
KW  - pharmacology
KW  - Breast Neoplasms
KW  - pathology
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - drug effects
KW  - Female
KW  - Fibroblasts
KW  - Glutamine
KW  - metabolism
KW  - Mechanistic Target of Rapamycin Complex 1
KW  - Mice, Knockout
KW  - Mice, Nude
KW  - Nucleotides
KW  - biosynthesis
KW  - Promoter Regions, Genetic
KW  - genetics
KW  - Signal Transduction
KW  - Sirtuin 3
KW  - deficiency
KW  - Small Molecule Libraries
KW  - Up-Regulation
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.celrep.2018.01.076
ER  -