TY - GEN AU - Montor,Wagner Ricardo AU - Salas,Andrei Ronaldo Oliveira Silva Escartin AU - Melo,Fabiana Henriques Machado de TI - Receptor tyrosine kinases and downstream pathways as druggable targets for cancer treatment: the current arsenal of inhibitors SN - 1476-4598 PY - 2019///0116 KW - Animals KW - Antineoplastic Combined Chemotherapy Protocols KW - adverse effects KW - Biomarkers, Tumor KW - Clinical Trials as Topic KW - Drug Discovery KW - Drug Resistance, Neoplasm KW - Humans KW - Molecular Targeted Therapy KW - Mutation KW - Neoplasms KW - drug therapy KW - Protein Binding KW - Protein Kinase Inhibitors KW - pharmacology KW - Receptor Protein-Tyrosine Kinases KW - antagonists & inhibitors KW - Signal Transduction KW - drug effects N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Review UR - https://doi.org/10.1186/s12943-018-0792-2 ER -