TY  - GEN
AU  - Park,Min Ju
AU  - Shen,Hailian
AU  - Spaeth,Jason M
AU  - Tolvanen,Jaana H
AU  - Failor,Courtney
AU  - Knudtson,Jennifer F
AU  - McLaughlin,Jessica
AU  - Halder,Sunil K
AU  - Yang,Qiwei
AU  - Bulun,Serdar E
AU  - Al-Hendy,Ayman
AU  - Schenken,Robert S
AU  - Aaltonen,Lauri A
AU  - Boyer,Thomas G
TI  - Oncogenic exon 2 mutations in Mediator subunit MED12 disrupt allosteric activation of cyclin C-CDK8/19
SN  - 1083-351X
PY  - 2019///0408
KW  - Allosteric Regulation
KW  - Cyclin C
KW  - genetics
KW  - Cyclin-Dependent Kinase 8
KW  - Cyclin-Dependent Kinases
KW  - Exons
KW  - Female
KW  - Humans
KW  - Leiomyoma
KW  - Mediator Complex
KW  - Mutation
KW  - Myometrium
KW  - metabolism
KW  - Neoplasm Proteins
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural
UR  - https://doi.org/10.1074/jbc.RA118.001725
ER  -