TY  - GEN
AU  - Komada,Takanori
AU  - Chung,Hyunjae
AU  - Lau,Arthur
AU  - Platnich,Jaye M
AU  - Beck,Paul L
AU  - Benediktsson,Hallgrimur
AU  - Duff,Henry J
AU  - Jenne,Craig N
AU  - Muruve,Daniel A
TI  - Macrophage Uptake of Necrotic Cell DNA Activates the AIM2 Inflammasome to Regulate a Proinflammatory Phenotype in CKD
SN  - 1533-3450
PY  - 2019///0916
KW  - Animals
KW  - Bone Marrow Transplantation
KW  - Caspase 1
KW  - metabolism
KW  - DNA
KW  - DNA-Binding Proteins
KW  - deficiency
KW  - Diabetic Nephropathies
KW  - Enzyme Activation
KW  - Fibrosis
KW  - Humans
KW  - Inflammasomes
KW  - physiology
KW  - Interleukin-1beta
KW  - Kidney Glomerulus
KW  - Kidney Tubules
KW  - Leukocytes
KW  - Macrophages
KW  - Male
KW  - Mice, Inbred C57BL
KW  - Mice, Knockout
KW  - Necrosis
KW  - Nephrosclerosis
KW  - Phagocytosis
KW  - Phenotype
KW  - Radiation Chimera
KW  - Renal Insufficiency, Chronic
KW  - THP-1 Cells
KW  - Ureteral Obstruction
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1681/ASN.2017080863
ER  -