Komada, Takanori <br/><br/>
Macrophage Uptake of Necrotic Cell DNA Activates the AIM2 Inflammasome to Regulate a Proinflammatory Phenotype in CKD.  [electronic resource] 

 -  Journal of the American Society of Nephrology : JASN  04 2018 
 - 1165-1181 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1533-3450 
<br/><br/><label>Standard No.: </label>10.1681/ASN.2017080863  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Bone Marrow Transplantation<br/>Caspase 1--metabolism<br/>DNA--metabolism<br/>DNA-Binding Proteins--deficiency<br/>Diabetic Nephropathies--metabolism<br/>Enzyme Activation<br/>Fibrosis<br/>Humans<br/>Inflammasomes--physiology<br/>Interleukin-1beta--metabolism<br/>Kidney Glomerulus--metabolism<br/>Kidney Tubules--metabolism<br/>Leukocytes--metabolism<br/>Macrophages--physiology<br/>Male<br/>Mice, Inbred C57BL<br/>Mice, Knockout<br/>Necrosis<br/>Nephrosclerosis--metabolism<br/>Phagocytosis<br/>Phenotype<br/>Radiation Chimera<br/>Renal Insufficiency, Chronic--metabolism<br/>THP-1 Cells<br/>Ureteral Obstruction--metabolism