Design of Highly Potent, Dual-Acting and Central-Nervous-System-Penetrating HIV-1 Protease Inhibitors with Excellent Potency against Multidrug-Resistant HIV-1 Variants. [electronic resource]
- ChemMedChem 04 2018
- 803-815 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
1860-7187
10.1002/cmdc.201700824 doi
Animals Brain--metabolism Carbamates--chemistry Cell Line Crystallography, X-Ray Drug Design HIV Infections--drug therapy HIV Protease--chemistry HIV Protease Inhibitors--chemistry HIV-1--chemistry Halogenation Humans Models, Molecular Rats