TY - GEN AU - Diao,Guoqing AU - Dong,Jun AU - Zeng,Donglin AU - Ke,Chunlei AU - Rong,Alan AU - Ibrahim,Joseph G TI - Biomarker threshold adaptive designs for survival endpoints SN - 1520-5711 PY - 2019///1025 KW - Algorithms KW - Antineoplastic Agents KW - therapeutic use KW - Antineoplastic Agents, Immunological KW - Biomarkers, Tumor KW - genetics KW - Biostatistics KW - methods KW - Clinical Decision-Making KW - Clinical Trials, Phase III as Topic KW - Computer Simulation KW - Data Interpretation, Statistical KW - ErbB Receptors KW - antagonists & inhibitors KW - Head and Neck Neoplasms KW - drug therapy KW - Humans KW - Models, Statistical KW - Neoplasms KW - PTEN Phosphohydrolase KW - Panitumumab KW - Patient Selection KW - Precision Medicine KW - Predictive Value of Tests KW - Randomized Controlled Trials as Topic KW - Research Design KW - statistics & numerical data KW - Squamous Cell Carcinoma of Head and Neck KW - Survival Analysis KW - Time Factors KW - Treatment Outcome N1 - Publication Type: Journal Article UR - https://doi.org/10.1080/10543406.2018.1434191 ER -