TY - GEN AU - Laurini,Erik AU - Martinelli,Valentina AU - Lanzicher,Thomas AU - Puzzi,Luca AU - Borin,Daniele AU - Chen,Suet Nee AU - Long,Carlin S AU - Lee,Patrice AU - Mestroni,Luisa AU - Taylor,Matthew R G AU - Sbaizero,Orfeo AU - Pricl,Sabrina TI - Biomechanical defects and rescue of cardiomyocytes expressing pathologic nuclear lamins SN - 1755-3245 PY - 2019///0827 KW - Animals KW - Animals, Newborn KW - Biomechanical Phenomena KW - Cardiomyopathies KW - genetics KW - Cells, Cultured KW - Elastic Modulus KW - Fluorescent Antibody Technique KW - Genetic Predisposition to Disease KW - Humans KW - Lamin Type A KW - chemistry KW - Microscopy, Atomic Force KW - Molecular Dynamics Simulation KW - Mutation KW - Myocardial Contraction KW - Myocytes, Cardiac KW - drug effects KW - Phenotype KW - Protein Conformation, alpha-Helical KW - Protein Kinase Inhibitors KW - pharmacology KW - Rats KW - Structure-Activity Relationship KW - p38 Mitogen-Activated Protein Kinases KW - antagonists & inhibitors N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1093/cvr/cvy040 ER -