Liu, Yuying

STAT3/p53 pathway activation disrupts IFN-β-induced dormancy in tumor-repopulating cells. [electronic resource] - The Journal of clinical investigation 03 2018 - 1057-1073 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1558-8238

10.1172/JCI96329 doi


Active Transport, Cell Nucleus
Animals
Cell Line, Tumor
Female
HEK293 Cells
Humans
Immune System
Indoleamine-Pyrrole 2,3,-Dioxygenase--metabolism
Interferon-beta--pharmacology
Kynurenine--metabolism
MCF-7 Cells
Melanoma, Experimental--metabolism
Mice
Mice, Inbred BALB C
Mice, Inbred C57BL
Mice, Inbred NOD
Mice, SCID
Neoplastic Stem Cells--cytology
Phosphorylation
Reactive Oxygen Species--metabolism
Receptors, Aryl Hydrocarbon--metabolism
STAT3 Transcription Factor--metabolism
Serine--chemistry
Signal Transduction
Tumor Suppressor Protein p53--metabolism
Tyrosine--chemistry