TY  - GEN
AU  - Zhang,Ning
AU  - Zoltner,Martin
AU  - Leung,Ka-Fai
AU  - Scullion,Paul
AU  - Hutchinson,Sebastian
AU  - Del Pino,Ricardo C
AU  - Vincent,Isabel M
AU  - Zhang,Yong-Kang
AU  - Freund,Yvonne R
AU  - Alley,Michael R K
AU  - Jacobs,Robert T
AU  - Read,Kevin D
AU  - Barrett,Michael P
AU  - Horn,David
AU  - Field,Mark C
TI  - Host-parasite co-metabolic activation of antitrypanosomal aminomethyl-benzoxaboroles
SN  - 1553-7374
PY  - 2018///0622
KW  - Activation, Metabolic
KW  - Aldehyde Dehydrogenase
KW  - antagonists & inhibitors
KW  - Aldehyde Oxidoreductases
KW  - Amine Oxidase (Copper-Containing)
KW  - Amino Acid Substitution
KW  - Animals
KW  - Boron Compounds
KW  - chemistry
KW  - Drug Resistance
KW  - High-Throughput Screening Assays
KW  - Humans
KW  - Models, Biological
KW  - Molecular Structure
KW  - Mutation
KW  - Phylogeny
KW  - Prodrugs
KW  - Protein Interaction Domains and Motifs
KW  - RNA Interference
KW  - Rats
KW  - Recombinant Fusion Proteins
KW  - Recombinant Proteins
KW  - Structure-Activity Relationship
KW  - Trypanocidal Agents
KW  - Trypanosoma brucei brucei
KW  - drug effects
N1  - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1371/journal.ppat.1006850
ER  -