Scheffel, Matthew J <br/><br/>
N-acetyl cysteine protects anti-melanoma cytotoxic T cells from exhaustion induced by rapid expansion via the downmodulation of Foxo1 in an Akt-dependent manner.  [electronic resource] 

 -  Cancer immunology, immunotherapy : CII  Apr 2018 
 - 691-702 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1432-0851 
<br/><br/><label>Standard No.: </label>10.1007/s00262-018-2120-5  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Acetylcysteine--pharmacology<br/>Animals<br/>Cells, Cultured<br/>Forkhead Box Protein O1--metabolism<br/>Free Radical Scavengers--pharmacology<br/>Gene Expression Regulation, Neoplastic--drug effects<br/>Humans<br/>Immunotherapy, Adoptive<br/>Lymphocyte Activation<br/>Melanoma--drug therapy<br/>Mice<br/>Phosphatidylinositol 3-Kinases--metabolism<br/>Proto-Oncogene Proteins c-akt--metabolism<br/>Signal Transduction<br/>T-Lymphocytes, Cytotoxic--immunology