TY  - GEN
AU  - Madan,Esha
AU  - Parker,Taylor M
AU  - Bauer,Matthias R
AU  - Dhiman,Alisha
AU  - Pelham,Christopher J
AU  - Nagane,Masaki
AU  - Kuppusamy,M Lakshmi
AU  - Holmes,Matti
AU  - Holmes,Thomas R
AU  - Shaik,Kranti
AU  - Shee,Kevin
AU  - Kiparoidze,Salome
AU  - Smith,Sean D
AU  - Park,Yu-Soon A
AU  - Gomm,Jennifer J
AU  - Jones,Louise J
AU  - Tomás,Ana R
AU  - Cunha,Ana C
AU  - Selvendiran,Karuppaiyah
AU  - Hansen,Laura A
AU  - Fersht,Alan R
AU  - Hideg,Kálmán
AU  - Gogna,Rajan
AU  - Kuppusamy,Periannan
TI  - The curcumin analog HO-3867 selectively kills cancer cells by converting mutant p53 protein to transcriptionally active wildtype p53
SN  - 1083-351X
PY  - 2019///0114
KW  - Animals
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Apoptosis
KW  - drug effects
KW  - Cell Proliferation
KW  - Curcumin
KW  - analogs & derivatives
KW  - Female
KW  - Humans
KW  - Mice
KW  - Mice, Nude
KW  - Mutant Proteins
KW  - genetics
KW  - Mutation
KW  - Neoplasms
KW  - drug therapy
KW  - Piperidones
KW  - Tumor Cells, Cultured
KW  - Tumor Suppressor Protein p53
KW  - Xenograft Model Antitumor Assays
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1074/jbc.RA117.000950
ER  -