Phoomvuthisarn, P

The CDK inhibitor purvalanol A induces neutrophil apoptosis and increases the turnover rate of Mcl-1: potential role of p38-MAPK in regulation of Mcl-1 turnover. [electronic resource] - Clinical and experimental immunology 05 2018 - 171-180 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1365-2249

10.1111/cei.13107 doi


Apoptosis--drug effects
Cells, Cultured
Gene Expression Regulation
Granulocyte-Macrophage Colony-Stimulating Factor--metabolism
Healthy Volunteers
Humans
Monocytes--drug effects
Myeloid Cell Leukemia Sequence 1 Protein--genetics
Naphthalenes--pharmacology
Neutrophils--drug effects
Proto-Oncogene Proteins c-akt--metabolism
Purines--pharmacology
Pyrazoles--pharmacology
Signal Transduction--drug effects
p38 Mitogen-Activated Protein Kinases--genetics