TY - GEN AU - Delgado-Enciso,Iván AU - López-Lemus,Uriel A AU - Valcarcel-Gamiño,Jose A AU - Rodriguez-Sanchez,Iram P AU - Valle-Reyes,Salvador AU - Martinez-Fierro,Margarita L AU - Melnikov,Valery AU - Guzmán-Esquivel,José AU - Vaca-Paniagua,Felipe AU - Valdez-Velazquez,Laura L AU - Baltazar-Rodriguez,Luz M AU - Soriano-Hernandez,Alejandro D AU - Paz-Michel,Brenda AU - Espinoza-Gómez,Francisco TI - Dengue virus-1 NS5 genetic variant associated with a severe clinical infection: Possible reduction of the innate immune response by inhibition of interferon type 1 and the Janus kinase-signal transducer and activator of transcription signaling pathway SN - 1791-244X PY - 2018///0823 KW - Adolescent KW - Adult KW - Aged KW - Aged, 80 and over KW - Child KW - Dengue KW - immunology KW - Dengue Virus KW - genetics KW - Female KW - Genetic Variation KW - Humans KW - Immunity, Innate KW - Interferon Type I KW - Janus Kinase 1 KW - Janus Kinases KW - Male KW - Middle Aged KW - Molecular Docking Simulation KW - Point Mutation KW - STAT Transcription Factors KW - Signal Transduction KW - Viral Nonstructural Proteins KW - Young Adult N1 - Publication Type: Journal Article UR - https://doi.org/10.3892/ijmm.2018.3395 ER -