Chang, Jian

Inhibition of COX-2 and 5-LOX regulates the progression of colorectal cancer by promoting PTEN and suppressing PI3K/AKT pathway. [electronic resource] - Biochemical and biophysical research communications 09 2019 - 1-7 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1090-2104

10.1016/j.bbrc.2018.01.061 doi


Animals
Arachidonate 5-Lipoxygenase--metabolism
Colorectal Neoplasms--metabolism
Cyclooxygenase 2 Inhibitors--pharmacology
Disease Progression
Humans
Lipoxygenase Inhibitors--pharmacology
Mice
PTEN Phosphohydrolase--drug effects
Phosphatidylinositol 3-Kinases--drug effects
Proto-Oncogene Proteins c-akt--drug effects
Signal Transduction--drug effects
Tumor Cells, Cultured