TY - GEN AU - Dubot,C AU - Bernard,V AU - Sablin,M P AU - Vacher,S AU - Chemlali,W AU - Schnitzler,A AU - Pierron,G AU - Ait Rais,K AU - Bessoltane,N AU - Jeannot,E AU - Klijanienko,J AU - Mariani,O AU - Jouffroy,T AU - Calugaru,V AU - Hoffmann,C AU - Lesnik,M AU - Badois,N AU - Berger,F AU - Le Tourneau,C AU - Kamal,M AU - Bieche,I TI - Comprehensive genomic profiling of head and neck squamous cell carcinoma reveals FGFR1 amplifications and tumour genomic alterations burden as prognostic biomarkers of survival SN - 1879-0852 PY - 2018///1023 KW - Adult KW - Aged KW - Biomarkers, Tumor KW - genetics KW - Carcinoma, Squamous Cell KW - Chi-Square Distribution KW - Cyclin D1 KW - Cyclin-Dependent Kinase Inhibitor p16 KW - Cyclin-Dependent Kinase Inhibitor p18 KW - DNA Copy Number Variations KW - Female KW - Gene Amplification KW - Gene Expression Profiling KW - methods KW - Genetic Predisposition to Disease KW - Head and Neck Neoplasms KW - High-Throughput Nucleotide Sequencing KW - Humans KW - Kaplan-Meier Estimate KW - Male KW - Middle Aged KW - Multivariate Analysis KW - Phenotype KW - Polymorphism, Single Nucleotide KW - Predictive Value of Tests KW - Proportional Hazards Models KW - Receptor, Fibroblast Growth Factor, Type 1 KW - Retrospective Studies KW - Risk Factors KW - Squamous Cell Carcinoma of Head and Neck KW - Time Factors KW - Transcriptome KW - Treatment Outcome KW - Tumor Suppressor Protein p53 KW - Young Adult N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.ejca.2017.12.016 ER -