Comprehensive genomic profiling of head and neck squamous cell carcinoma reveals FGFR1 amplifications and tumour genomic alterations burden as prognostic biomarkers of survival. [electronic resource]
- European journal of cancer (Oxford, England : 1990) 03 2018
- 47-55 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1879-0852
10.1016/j.ejca.2017.12.016 doi
Adult Aged Biomarkers, Tumor--genetics Carcinoma, Squamous Cell--genetics Chi-Square Distribution Cyclin D1--genetics Cyclin-Dependent Kinase Inhibitor p16 Cyclin-Dependent Kinase Inhibitor p18--genetics DNA Copy Number Variations Female Gene Amplification Gene Expression Profiling--methods Genetic Predisposition to Disease Head and Neck Neoplasms--genetics High-Throughput Nucleotide Sequencing Humans Kaplan-Meier Estimate Male Middle Aged Multivariate Analysis Phenotype Polymorphism, Single Nucleotide Predictive Value of Tests Proportional Hazards Models Receptor, Fibroblast Growth Factor, Type 1--genetics Retrospective Studies Risk Factors Squamous Cell Carcinoma of Head and Neck Time Factors Transcriptome Treatment Outcome Tumor Suppressor Protein p53--genetics Young Adult