Ruiz-García, Raquel

Mutations in PI3K110δ cause impaired natural killer cell function partially rescued by rapamycin treatment. [electronic resource] - The Journal of allergy and clinical immunology 08 2018 - 605-617.e7 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1097-6825

10.1016/j.jaci.2017.11.042 doi


Cell Differentiation
Cells, Cultured
Class I Phosphatidylinositol 3-Kinases
Cytomegalovirus--physiology
Cytomegalovirus Infections--genetics
Cytotoxicity, Immunologic--drug effects
Epstein-Barr Virus Infections--genetics
Herpesvirus 4, Human--physiology
Heterozygote
Humans
Immunologic Deficiency Syndromes--drug therapy
Immunological Synapses--metabolism
Immunophenotyping
Killer Cells, Natural--physiology
Lymphocyte Activation
Microscopy, Confocal
Mutation--genetics
Phosphatidylinositol 3-Kinases--genetics
Sirolimus--therapeutic use
Viremia
Exome Sequencing