Ouvry, Gilles <br/><br/>
Discovery and Characterization of CD12681, a Potent RORγ Inverse Agonist, Preclinical Candidate for the Topical Treatment of Psoriasis.  [electronic resource] 

 -  ChemMedChem  02 2018 
 - 321-337 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1860-7187 
<br/><br/><label>Standard No.: </label>10.1002/cmdc.201700758  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Administration, Topical<br/>Animals<br/>Disease Models, Animal<br/>Drug Evaluation, Preclinical<br/>Drug Inverse Agonism<br/>Humans<br/>Inhibitory Concentration 50<br/>Interleukin-17--metabolism<br/>Interleukin-23--pharmacology<br/>Keratinocytes--cytology<br/>Mice<br/>Mice, Inbred BALB C<br/>Nuclear Receptor Subfamily 1, Group F, Member 3--agonists<br/>Psoriasis--drug therapy<br/>Skin Diseases--chemically induced<br/>Structure-Activity Relationship<br/>Sulfonamides--chemistry<br/>Th17 Cells--cytology